In 2020, the Regional Refugee and Resilience Plan (3RP) seeks a total of US$ 6 billion to support over 5.5 million registered Syrian refugees in Turkey, Lebanon, Jordan, Iraq and Egypt in support of national efforts, as well as 4.5 million host community members. Over the last ten years, these host countries have generously hosted Syrian refugees despite the challenging economic situations in which poverty rates were already high. The majority of refugee men, women, girls, and boys and vulnerable host communities were already living on or beneath national poverty levels before COVID-19 and the outbreak of the pandemic has exacerbated these pre-existing protection risks and socio-economic challenges especially for Syrian girls and women who are the most affected by COVID-19. It also puts the economies, services and infrastructure of host countries and communities even further under strain.